A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...
Topological defects are universal patterns of nature. Nematic liquid crystals are ideal test beds for studying defects, particularly one-dimensional, linear disclinations. Predicting the structure of ...
Long noncoding RNA MALAT1 is dynamically regulated in leader cells during collective cancer invasion
The prevalence of collective cancer invasion as a mechanism of cancer metastasis is widely reported, but the regulatory mechanisms at the invading fronts of tumors remain largely unknown. Conflicting ...
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