The American Journal of Managed Care

ESR1 Mutation Testing and Precision Medicine in Patients With ER+/HER2- Metastatic Breast Cancer

Experts discuss the necessity of ESR1 mutation testing when considering treatment with elacestrant in patients with estrogen receptor–positive (ER+)/HER2-negative (HER2–) metastatic breast cancer and ...
The American Journal of Managed Care

HER2- Mutation Testing Considerations and Timing

Integrating HER2-directed therapies into NSCLC decision-making requires adapting protocols and ensuring timely updates as new therapies emerge. Streamlined processes and enhanced communication among ...
Business Insider

I got tested for the BRCA2 gene mutation after my mom was diagnosed with breast cancer. A simple test gave me peace of mind.

I was 18 when my mom was diagnosed with breast cancer. It altered the trajectory of my second year at college and changed how I viewed my mom, whom I naively thought was exempt from harm. She knew ...
Nature

Patient-centric thresholding of Cobas® EGFR mutation Test v2 for surveillance of EGFR-mutated metastatic non-small cell lung cancer

Circulating tumor (ctDNA) is increasingly used for cancer diagnosis and monitoring. ESMO and ASCO recognize the clinical utility of liquid biopsy for diagnostic purposes and to identify actionable ...
Kaleido Scope

Known Mutation Testing (KT2)

We offer targeted detection of a previously characterized mutation within the family. From a fresh EDTA blood sample, DNA is extracted directly and the target region is amplified and directly ...
Healthline

Muscular Dystrophy and Genetic Testing: Your Questions Answered

Genetic testing can confirm a muscular dystrophy (MD) diagnosis when symptoms and other tests already suggest MD. It also identifies specific gene mutations that can guide targeted treatment. Genetic ...
ascopubs.org

Podcast: Testing for ESR1 Mutations to Guide Therapy for HR-Positive, HER2-Negative Metastatic Breast Cancer Rapid Recommendation Update

Dr. Angie DeMichele and Dr. Lynn Henry present the latest rapid recommendation impacting two ASCO guidelines. This update focuses on testing for ESR1 mutations in patients with hormone ...
Nature

Successful birth after preimplantation genetic testing for rare mitochondrial DNA mutation m.10197G>A

Here we report the first successful birth after preimplantation genetic testing for m.10197G>A mutation, a rare variant responsible for Leigh encephalopathy. Preimplantation genetic testing diagnosed ...
Forbes

Leveraging Generative AI For Enhanced Efficiency, Accuracy And Scalability In Chaos And Mutation Testing

Deepak Gupta, VP Engineering at Cars24. Specializes in FinTech, AI/ML, E-comm, digital transformation, business strategy and revenue growth. Software systems are getting more complex, like a giant ...