We developed SpaceBar, a method that uses DNA barcodes to label both individual cells and their progeny and seamlessly integrates with high-resolution imaging-based spatial transcriptomics ...
All-optical voltage imaging-guided postsynaptic single-cell transcriptome profiling with Voltage-Seq
Neuronal pathways recruit large postsynaptic populations and maintain connections via distinct postsynaptic response types (PRTs). Until recently, PRTs were accessible as a selection criterion for ...
Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...
Scientists at St. Jude Children's Research Hospital, the National Center for Genomic Analysis and the University of Adelaide have created a single-cell RNA analysis method that is 47 times cheaper and ...
In a recent study published in Nature Communications, a team of researchers at the Carl R. Woese Institute for Genomic Biology reports a new, robust computational toolset to extract biological ...
Although numerous spatial transcriptomics analyses exist for evaluating RNA localization, these methods face several limitations. Cell fractionation techniques, such as density gradient centrifugation ...
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